|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alias
|
gptkb:IRP
gptkb:WNT2A
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:cancer
lung development
|
|
gptkbp:biologicalProcess
|
signaling molecule
|
|
gptkbp:database
|
gptkb:GeneCards
gptkb:NCBI_Gene
gptkb:UniProt
|
|
gptkbp:discoveredBy
|
gptkb:Nusse_and_Varmus
|
|
gptkbp:encodedBy
|
gptkb:WNT2_gene
|
|
gptkbp:Entrez_Gene_ID
|
7472
|
|
gptkbp:expressedIn
|
gptkb:cancer
gptkb:placenta
brain
heart
|
|
gptkbp:firstDescribed
|
1982
|
|
gptkbp:foundIn
|
gptkb:Homo_sapiens
|
|
gptkbp:function
|
signaling protein
|
|
gptkbp:gene
|
gptkb:WNT2
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
12784
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Wnt2
|
|
gptkbp:interactsWith
|
gptkb:Frizzled_receptors
gptkb:LRP5/6
|
|
gptkbp:involvedIn
|
gptkb:Wnt_signaling_pathway
|
|
gptkbp:length
|
360 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_7q31
|
|
gptkbp:memberOf
|
gptkb:Wnt_family
|
|
gptkbp:molecularWeight
|
40 kDa
|
|
gptkbp:mutationAssociatedWith
|
colorectal cancer
gastric cancer
pulmonary arterial hypertension
|
|
gptkbp:OMIM
|
147870
|
|
gptkbp:orthologIn
|
gptkb:Danio_rerio
gptkb:Mus_musculus
|
|
gptkbp:postTranslationalModification
|
palmitoylation
glycosylation
|
|
gptkbp:proteinFamily
|
gptkb:Wnt_proteins
|
|
gptkbp:regulates
|
gptkb:beta-catenin
cell signaling
|
|
gptkbp:relatedTo
|
gptkb:Wnt1
gptkb:Wnt2b
gptkb:Wnt3
|
|
gptkbp:role
|
cell proliferation
embryonic development
cell fate determination
|
|
gptkbp:subcellularLocation
|
secreted
|
|
gptkbp:UniProtID
|
P09544
|
|
gptkbp:bfsParent
|
gptkb:WNT2
|
|
gptkbp:bfsLayer
|
7
|