|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:associatedWith
|
gptkb:cancer
developmental disorders
|
|
gptkbp:discoveredIn
|
1982
|
|
gptkbp:encodes
|
gptkb:Wnt_proteins
|
|
gptkbp:example
|
gptkb:WNT1
gptkb:WNT10B
gptkb:WNT2
gptkb:WNT3
gptkb:WNT4
gptkb:WNT5A
gptkb:WNT7A
gptkb:WNT8A
|
|
gptkbp:foundIn
|
animals
|
|
gptkbp:involvedIn
|
gptkb:Wnt_signaling_pathway
|
|
gptkbp:locatedOnChromosome
|
various chromosomes in humans
|
|
gptkbp:mutationAssociatedWith
|
gptkb:cancer
gptkb:tetra-amelia_syndrome
gptkb:bone
colorectal cancer
|
|
gptkbp:namedAfter
|
Wingless (Drosophila) and Int-1 (mouse)
|
|
gptkbp:numberOfMembers
|
19 in humans
|
|
gptkbp:orthologIn
|
invertebrates
vertebrates
|
|
gptkbp:pathway
|
canonical (β-catenin dependent)
non-canonical (β-catenin independent)
|
|
gptkbp:proteinProductType
|
secreted glycoprotein
|
|
gptkbp:recipient
|
gptkb:Frizzled_family
|
|
gptkbp:regulates
|
gptkb:immune_response
apoptosis
cell proliferation
embryonic development
angiogenesis
cell migration
axis patterning
bone formation
cell fate determination
neurogenesis
organogenesis
stem cell maintenance
cell polarity
cell adhesion
myogenesis
adipogenesis
hair follicle development
limb development
synapse formation
|
|
gptkbp:bfsParent
|
gptkb:Wnt_ligands
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
WNT genes
|