|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:discoveredBy
|
gptkb:Roel_Nusse
|
|
gptkbp:encodes
|
gptkb:Wnt-4_protein
|
|
gptkbp:Entrez_Gene_ID
|
54361
ENSG00000162552
|
|
gptkbp:expressedIn
|
gptkb:adrenal_gland
gptkb:kidney
gptkb:testis
|
|
gptkbp:firstDescribed
|
1990
|
|
gptkbp:HGNC_ID
|
12786
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
WNT4
|
|
gptkbp:inhibitedBy
|
testis development in XX individuals
|
|
gptkbp:involvedIn
|
embryonic development
cell signaling
kidney development
female sex determination
gonadal development
urogenital system development
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_1p36.12
|
|
gptkbp:memberOf
|
gptkb:WNT_gene_family
|
|
gptkbp:mutationAssociatedWith
|
gptkb:46,XX_sex_reversal
gptkb:SERKAL_syndrome
Müllerian duct regression
|
|
gptkbp:OMIM
|
603490
|
|
gptkbp:orthologInMouse
|
gptkb:Wnt4
|
|
gptkbp:pathway
|
gptkb:Wnt_signaling_pathway
canonical Wnt pathway
non-canonical Wnt pathway
|
|
gptkbp:product
|
secreted signaling protein
|
|
gptkbp:proteinFamily
|
gptkb:Wnt_family
|
|
gptkbp:regulates
|
cell proliferation
cell migration
organogenesis
cell fate
cell polarity
Müllerian duct formation
adrenal development
anti-testis pathway
gonadal differentiation
mesonephric duct development
nephron development
ovarian follicle development
sex differentiation
|
|
gptkbp:relatedTo
|
gptkb:WNT3A
gptkb:WNT1
gptkb:WNT5A
gptkb:WNT7A
gptkb:WNT8A
|
|
gptkbp:UniProtID
|
P56705
|
|
gptkbp:bfsParent
|
gptkb:WNT
|
|
gptkbp:bfsLayer
|
6
|