|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:associatedWith
|
gptkb:46,XX_sex_reversal
gptkb:SERKAL_syndrome
gptkb:Müllerian_aplasia
kidney dysgenesis
|
|
gptkbp:discoveredBy
|
gptkb:Nusse_and_Varmus
|
|
gptkbp:encodes
|
gptkb:Wnt4_protein
|
|
gptkbp:Entrez_Gene_ID
|
54361
ENSG00000162552
|
|
gptkbp:expressedIn
|
gptkb:kidney
gptkb:testis
embryonic tissues
|
|
gptkbp:fullName
|
gptkb:Wnt_family_member_4
|
|
gptkbp:function
|
embryonic development
cell signaling
sex determination
kidney development
gonadal development
|
|
gptkbp:HGNC_ID
|
12786
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Wnt4
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_1p36.12_(human)
|
|
gptkbp:memberOf
|
gptkb:Wnt_gene_family
|
|
gptkbp:mutationAssociatedWith
|
gptkb:46,XX_sex_reversal
gptkb:SERKAL_syndrome
Müllerian duct regression
|
|
gptkbp:OMIM
|
603490
|
|
gptkbp:orthologInMouse
|
gptkb:Wnt4
|
|
gptkbp:orthologInZebrafish
|
gptkb:wnt4b
wnt4a
|
|
gptkbp:pathway
|
gptkb:Wnt_signaling_pathway
canonical Wnt pathway
non-canonical Wnt pathway
|
|
gptkbp:postTranslationalModification
|
palmitoylation
glycosylation
|
|
gptkbp:product
|
secreted glycoprotein
|
|
gptkbp:recipient
|
gptkb:Frizzled_family_receptors
|
|
gptkbp:regulates
|
cell proliferation
cell migration
cell fate determination
cell polarity
β-catenin signaling
female sex differentiation
gonadal ridge formation
mesonephric development
nephron formation
|
|
gptkbp:symbol
|
gptkb:WNT4
|
|
gptkbp:UniProtID
|
P56705
|
|
gptkbp:bfsParent
|
gptkb:WNT4
|
|
gptkbp:bfsLayer
|
7
|