Bladder cancer

GPTKB entity

Statements (50)
Predicate Object
gptkbp:instanceOf gptkb:cancer
gptkbp:affectsOrgan bladder
gptkbp:associatedWith gptkb:bladder_stones
urinary tract infection
gptkbp:canMetastasizeTo lungs
liver
lymph nodes
bones
gptkbp:commonIn industrial workers exposed to aromatic amines
gptkbp:diagnosedBy urinalysis
biopsy
cystoscopy
imaging tests
gptkbp:firstDescribed 19th century
gptkbp:geneticStudies gptkb:TP53_mutation
FGFR3 mutation
https://www.w3.org/2000/01/rdf-schema#label Bladder cancer
gptkbp:ICD-10_code gptkb:C67
gptkbp:incidence estimated 573,000 new cases worldwide in 2020
high in developed countries
gptkbp:lessCommonType gptkb:cancer
gptkbp:mortalityRate high if advanced
gptkbp:prevalence more common in men
more common in older adults
gptkbp:prevention avoid smoking
limit exposure to chemicals
gptkbp:prognosis varies by stage
gptkbp:recurrence common
gptkbp:recurrenceMonitoring regular cystoscopy
gptkbp:riskFactor smoking
chronic bladder inflammation
exposure to industrial chemicals
family history of bladder cancer
gptkbp:screening not routine for general population
gptkbp:specialty oncology
urology
gptkbp:stagingSystem gptkb:TNM
gptkbp:symptom frequent urination
blood in urine
painful urination
gptkbp:treatment gptkb:BCG_vaccine_(as_immunotherapy)
surgery
radiation therapy
chemotherapy
immunotherapy
intravesical therapy
gptkbp:type gptkb:urothelial_carcinoma
gptkbp:victim estimated 212,000 deaths worldwide in 2020
gptkbp:bfsParent gptkb:UniProt:P01112
gptkbp:bfsLayer 5