|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:non-small_cell_lung_cancer
gptkb:glioblastoma
colorectal cancer
head and neck cancer
|
|
gptkbp:biologicalProcess
|
cell differentiation
cell proliferation
signal transduction
|
|
gptkbp:cellularComponent
|
gptkb:plasma_membrane
|
|
gptkbp:encodedBy
|
gptkb:EGFR_gene
|
|
gptkbp:function
|
receptor tyrosine kinase involved in cell proliferation and differentiation
|
|
gptkbp:gene
|
gptkb:EGFR
|
|
gptkbp:hasIsoform
|
gptkb:EGFR_protein
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
NP 005334.1
|
|
gptkbp:length
|
1210 amino acids
|
|
gptkbp:ligand
|
gptkb:epidermal_growth_factor_(EGF)
gptkb:transforming_growth_factor_alpha_(TGF-α)
|
|
gptkbp:locatedOnChromosome
|
gptkb:7p11.2
|
|
gptkbp:molecularWeight
|
134 kDa
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:pathway
|
gptkb:JAK-STAT_signaling_pathway
gptkb:MAPK_signaling_pathway
gptkb:PI3K-Akt_signaling_pathway
|
|
gptkbp:postTranslationalModification
|
phosphorylation
glycosylation
|
|
gptkbp:protein_name
|
gptkb:epidermal_growth_factor_receptor_isoform_1_precursor
|
|
gptkbp:RefSeq
|
gptkb:NP_005334.1
|
|
gptkbp:sequenceStatus
|
reviewed
|
|
gptkbp:subcellularLocation
|
gptkb:cell_membrane
|
|
gptkbp:UniProtID
|
gptkb:P00533
|
|
gptkbp:bfsParent
|
gptkb:UniProt:P01112
|
|
gptkbp:bfsLayer
|
5
|