|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:discoveredBy
|
Hsu et al.
|
|
gptkbp:discoveredIn
|
1996
|
|
gptkbp:domain
|
coiled-coil domain
RING-type zinc finger
MATH domain
|
|
gptkbp:Entrez_Gene_ID
|
ENSG00000175104
|
|
gptkbp:expressedIn
|
ubiquitous
|
|
gptkbp:fullName
|
TNF receptor-associated factor 6
|
|
gptkbp:function
|
gptkb:E3_ubiquitin-protein_ligase
signal transduction
|
|
gptkbp:gene
|
gptkb:TRAF6
|
|
gptkbp:HGNC_ID
|
HGNC:12031
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
TRAF6
|
|
gptkbp:interactsWith
|
gptkb:TAK1
gptkb:TANK
gptkb:CD40
gptkb:RANK
gptkb:TAB2
gptkb:TRAF2
gptkb:TRAF5
TRAF3
IRAK1
MyD88
|
|
gptkbp:involvedIn
|
gptkb:Toll-like_receptor_signaling_pathway
gptkb:NF-kappaB_signaling_pathway
IL-1 receptor signaling pathway
|
|
gptkbp:locatedOnChromosome
|
gptkb:11p12
|
|
gptkbp:molecularWeight
|
approximately 60 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:osteopetrosis
immunodeficiency
|
|
gptkbp:OMIM
|
602355
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Traf6
|
|
gptkbp:postTranslationalModification
|
phosphorylation
ubiquitination
|
|
gptkbp:UniProtID
|
Q9Y4K3
|
|
gptkbp:bfsParent
|
gptkb:Death_Domain
gptkb:TNFAIP3
gptkb:EDARADD
|
|
gptkbp:bfsLayer
|
7
|