Statements (24)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:cofactor |
ubiquitin
|
| gptkbp:discoveredIn |
1990s
|
| gptkbp:EC_number |
2.3.2.27
|
| gptkbp:foundIn |
eukaryotes
|
| gptkbp:function |
catalyzes transfer of ubiquitin to substrate proteins
|
| gptkbp:GO_term |
gptkb:GO:0061630
|
| https://www.w3.org/2000/01/rdf-schema#label |
E3 ubiquitin-protein ligase
|
| gptkbp:interactsWith |
gptkb:E2_ubiquitin-conjugating_enzyme
substrate proteins |
| gptkbp:involvedIn |
gptkb:ubiquitin-proteasome_pathway
|
| gptkbp:relatedTo |
protein homeostasis
cellular quality control |
| gptkbp:role |
signal transduction
DNA repair cell cycle regulation protein degradation regulation of protein turnover |
| gptkbp:subspecies |
gptkb:HECT_domain_E3_ligases
gptkb:RING_finger_E3_ligases gptkb:U-box_E3_ligases |
| gptkbp:bfsParent |
gptkb:NEDD4-1
gptkb:CHIP |
| gptkbp:bfsLayer |
6
|