|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alias
|
gptkb:TAK1
gptkb:MEKK7
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:cancer
inflammatory diseases
cardiac hypertrophy
|
|
gptkbp:discoveredBy
|
Yamaguchi et al.
|
|
gptkbp:discoveredIn
|
1995
|
|
gptkbp:encodes
|
gptkb:TAK1
|
|
gptkbp:Entrez_Gene_ID
|
6885
ENSG00000076928
|
|
gptkbp:expressedIn
|
many tissues
|
|
gptkbp:fullName
|
Mitogen-activated protein kinase kinase kinase 7
|
|
gptkbp:function
|
serine/threonine kinase activity
|
|
gptkbp:HGNC_ID
|
6859
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
MAP3K7
|
|
gptkbp:interactsWith
|
gptkb:TRAF6
gptkb:TAB1
gptkb:TAB2
gptkb:TAB3
TAK1-binding protein 1
|
|
gptkbp:involvedIn
|
gptkb:TGF-beta_signaling_pathway
gptkb:MAPK_signaling_pathway
gptkb:NF-kappaB_signaling_pathway
|
|
gptkbp:length
|
606
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_6
|
|
gptkbp:molecularWeight
|
66 kDa
|
|
gptkbp:mutationAssociatedWith
|
frontometaphyseal dysplasia 2
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Map3k7
|
|
gptkbp:PDB
|
gptkb:2EVA
|
|
gptkbp:phosphorylates
|
gptkb:MAP2K6
gptkb:MAP2K4
gptkb:TAB1
IKBKG
|
|
gptkbp:postTranslationalModification
|
phosphorylation
ubiquitination
|
|
gptkbp:regulates
|
apoptosis
cell differentiation
inflammation
immune response
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:UniProtID
|
O43318
|
|
gptkbp:bfsParent
|
gptkb:MAP2K3
gptkb:MAP2K6
gptkb:MKK6
gptkb:TAK1
|
|
gptkbp:bfsLayer
|
7
|