|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alternativeName
|
RNF123
TRAF-2
Tumor necrosis factor receptor-associated factor 2
|
|
gptkbp:associatedWith
|
gptkb:cancer
autoimmune diseases
inflammatory diseases
|
|
gptkbp:cellularComponent
|
gptkb:nucleus
gptkb:cytoplasm
cytosol
|
|
gptkbp:discoveredIn
|
1995
|
|
gptkbp:domain
|
coiled-coil domain
RING-type zinc finger
TRAF domain
|
|
gptkbp:encodedBy
|
TRAF2 gene
|
|
gptkbp:Entrez_Gene_ID
|
7186
ENSG00000013588
|
|
gptkbp:fullName
|
TNF receptor-associated factor 2
|
|
gptkbp:function
|
signal transduction
immune response
apoptosis regulation
regulation of NF-kappaB
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
TRAF2
|
|
gptkbp:interactsWith
|
gptkb:TNF_receptor
gptkb:TRADD
gptkb:RIPK1
gptkb:TRAF1
gptkb:TRAF5
gptkb:cIAP1
gptkb:cIAP2
TRAF3
|
|
gptkbp:locatedOnChromosome
|
9q34.3
|
|
gptkbp:molecularWeight
|
56 kDa
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Traf2
|
|
gptkbp:pathway
|
gptkb:TNF_signaling_pathway
gptkb:NF-kappaB_signaling_pathway
apoptosis pathway
|
|
gptkbp:postTranslationalModification
|
phosphorylation
ubiquitination
|
|
gptkbp:regulates
|
apoptosis
cell survival
inflammatory response
MAPK8/JNK pathway
|
|
gptkbp:reviewedBy
|
gptkb:NCBI_Gene
gptkb:UniProt
gptkb:Ensembl
|
|
gptkbp:subunit
|
TRAF protein complex
|
|
gptkbp:UniProtID
|
Q12933
|
|
gptkbp:bfsParent
|
gptkb:Death_Domain
gptkb:TNFAIP3
gptkb:MAP3K1
gptkb:MAP4K1
gptkb:TNFR1
gptkb:TNFR2
|
|
gptkbp:bfsLayer
|
7
|