Statements (34)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:abbreviation |
TRAF
|
| gptkbp:binds |
gptkb:TNF_receptor_superfamily
interleukin-1 receptor/Toll-like receptor |
| gptkbp:discoveredBy |
1990s
|
| gptkbp:domain |
zinc finger domain
RING finger domain TRAF domain |
| gptkbp:fullName |
TNF receptor-associated factors
|
| gptkbp:function |
signal transduction
regulation of immune response activation of MAPK pathway activation of NF-κB pathway |
| https://www.w3.org/2000/01/rdf-schema#label |
TRAF proteins
|
| gptkbp:involvedIn |
inflammation
innate immunity apoptosis regulation adaptive immunity |
| gptkbp:locatedOnChromosome |
varies by member
|
| gptkbp:member |
gptkb:TRAF6
gptkb:TRAF2 gptkb:TRAF1 gptkb:TRAF5 TRAF3 TRAF4 |
| gptkbp:orthologIn |
found in birds
found in fish found in invertebrates found in mammals |
| gptkbp:relatedTo |
gptkb:cancer
autoimmune diseases ubiquitination |
| gptkbp:bfsParent |
gptkb:CD30
|
| gptkbp:bfsLayer |
7
|