Toll-like receptor signaling pathway
GPTKB entity
Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
biological pathway
|
| gptkbp:activatedBy |
gptkb:MAPK_pathway
gptkb:NF-κB_pathway IRF pathway |
| gptkbp:cause |
autoimmune diseases
inflammatory response cytokine production chronic inflammation |
| gptkbp:describedBy |
KEGG pathway hsa04620
Reactome R-HSA-168164 |
| https://www.w3.org/2000/01/rdf-schema#label |
Toll-like receptor signaling pathway
|
| gptkbp:involves |
gptkb:TLR2
gptkb:TLR4 gptkb:Toll-like_receptors gptkb:TRAF6 gptkb:TLR3 gptkb:TLR9 gptkb:IRAK4 TLR7 MyD88 TRIF |
| gptkbp:launched |
pathogen-associated molecular patterns
damage-associated molecular patterns |
| gptkbp:partOf |
immune system
|
| gptkbp:regulates |
adaptive immune response
innate immune response |
| gptkbp:studiedBy |
immunology
|
| gptkbp:target |
therapeutic drugs
|
| gptkbp:bfsParent |
gptkb:TLR4
gptkb:MAPK14 gptkb:TLR4_gene |
| gptkbp:bfsLayer |
7
|