Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
RING E3 ligase
RING finger E3 ubiquitin ligase |
| gptkbp:catalyzes |
transfer of ubiquitin from E2 enzyme to substrate protein
|
| gptkbp:discoveredIn |
1990s
|
| gptkbp:domain |
RING finger domain
|
| gptkbp:enzymeCommissionNumber |
EC 6.3.2.-
|
| gptkbp:example |
gptkb:RNF8
gptkb:MDM2 gptkb:BRCA1 gptkb:TRAF6 gptkb:c-Cbl |
| gptkbp:foundIn |
eukaryotes
|
| gptkbp:function |
ubiquitin ligase activity
|
| https://www.w3.org/2000/01/rdf-schema#label |
RING-type ubiquitin ligase
|
| gptkbp:involvedIn |
ubiquitination
|
| gptkbp:recognizedBy |
zinc ion binding
|
| gptkbp:regulates |
signal transduction
DNA repair cell cycle protein degradation |
| gptkbp:bfsParent |
gptkb:ubiquitin_ligase
|
| gptkbp:bfsLayer |
7
|