Statements (54)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alsoKnownAs |
HNF-3-alpha
|
| gptkbp:associatedWith |
gptkb:cancer
prostate cancer |
| gptkbp:binds |
gptkb:gene
|
| gptkbp:domain |
forkhead domain
|
| gptkbp:encodes |
FOXA1 protein
|
| gptkbp:Entrez_Gene_ID |
3169
ENSG00000129514 |
| gptkbp:expressedIn |
gptkb:prostate
liver pancreas breast tissue |
| gptkbp:fullName |
Forkhead box protein A1
|
| gptkbp:function |
transcription factor
|
| gptkbp:HGNC_ID |
HGNC:5021
|
| https://www.w3.org/2000/01/rdf-schema#label |
FOXA1
|
| gptkbp:involvedIn |
development of liver
development of pancreas development of prostate |
| gptkbp:locatedOnChromosome |
14q21.1
|
| gptkbp:memberOf |
forkhead box (FOX) family
|
| gptkbp:mutationAssociatedWith |
aggressive prostate cancer
endocrine resistance in breast cancer |
| gptkbp:OMIM |
602294
|
| gptkbp:orthologInMouse |
Foxa1
|
| gptkbp:regulates |
cell differentiation
cell proliferation gene expression cell migration chromatin structure cellular metabolism hormone response cell invasion GATA3 expression androgen receptor signaling estrogen receptor signaling mammary gland development insulin gene expression pancreatic beta cell development AR (androgen receptor) expression ERα (ESR1) expression SHBG gene expression endoderm development epithelial cell fate glucagon gene expression hepatocyte differentiation luminal cell identity prostate gland development |
| gptkbp:UniProtID |
P55317
|
| gptkbp:bfsParent |
gptkb:Forkhead_box_(FOX)_protein_family
gptkb:Androgen_receptor gptkb:miR-194 |
| gptkbp:bfsLayer |
7
|