|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alias
|
gptkb:CK18
K18
Cytokeratin 18
|
|
gptkbp:associatedWith
|
gptkb:liver_disease
cirrhosis
non-alcoholic steatohepatitis
|
|
gptkbp:discoveredBy
|
molecular biology research
|
|
gptkbp:encodes
|
Keratin 18 protein
|
|
gptkbp:Entrez_Gene_ID
|
3875
ENSG00000111057
GC12M053774
|
|
gptkbp:expressedIn
|
epithelial cells
|
|
gptkbp:formsHeterodimerWith
|
gptkb:KRT8
|
|
gptkbp:foundIn
|
gptkb:cytoplasm
|
|
gptkbp:fullName
|
Keratin, type I cytoskeletal 18
|
|
gptkbp:function
|
structural component of the cytoskeleton
|
|
gptkbp:hasBiomarker
|
apoptosis
liver injury
|
|
gptkbp:HGNC_ID
|
HGNC:6436
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
KRT18
|
|
gptkbp:length
|
430 amino acids
|
|
gptkbp:locatedOnChromosome
|
12
12q13.13
|
|
gptkbp:molecularWeight
|
48 kDa
|
|
gptkbp:mutationAssociatedWith
|
liver disorders
|
|
gptkbp:OMIM
|
148070
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Krt18
|
|
gptkbp:postTranslationalModification
|
phosphorylation
caspase cleavage
|
|
gptkbp:proteinFamily
|
gptkb:keratin_family
|
|
gptkbp:Reactome
|
R-HSA-6805567
|
|
gptkbp:relatedTo
|
cellular stress response
tissue homeostasis
cell death
epithelial cell integrity
|
|
gptkbp:subcellularLocation
|
intermediate filament
|
|
gptkbp:UniProtID
|
P05783
|
|
gptkbp:bfsParent
|
gptkb:KRT8
|
|
gptkbp:bfsLayer
|
7
|