|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alias
|
PKC-zeta
PKC2
nPKC-zeta
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:Alzheimer's_disease
gptkb:cancer
gptkb:diabetes_mellitus
|
|
gptkbp:biologicalProcess
|
gptkb:NF-kappaB_signaling_pathway
cell signaling
ATP binding
insulin signaling pathway
protein kinase activity
cell polarity establishment
|
|
gptkbp:cellularComponent
|
gptkb:nucleus
gptkb:cytoplasm
gptkb:plasma_membrane
|
|
gptkbp:discoveredBy
|
Ohno S et al.
|
|
gptkbp:discoveredIn
|
1990
|
|
gptkbp:encodes
|
Protein kinase C zeta type
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000163599
5590
|
|
gptkbp:enzyme
|
true
|
|
gptkbp:function
|
signal transduction
regulation of cell proliferation
serine/threonine-protein kinase activity
regulation of cell polarity
|
|
gptkbp:gene
|
gptkb:PRKCZ
|
|
gptkbp:HGNC_ID
|
9401
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
PRKCZ
|
|
gptkbp:interactsWith
|
gptkb:AKT1
gptkb:CDC42
gptkb:RAC1
gptkb:PAR-3
gptkb:PAR-6
NFKBIA
PARD6A
RELA
|
|
gptkbp:isKinase
|
true
|
|
gptkbp:locatedOnChromosome
|
chromosome 1
1p36.33
|
|
gptkbp:OMIM
|
600937
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Prkcz
|
|
gptkbp:phosphorylates
|
gptkb:PAR-3
gptkb:PAR-6
NFKBIA
RELA
|
|
gptkbp:proteinFamily
|
gptkb:protein_kinase_C_family
atypical PKC subfamily
|
|
gptkbp:refSeqID
|
NM_002744
|
|
gptkbp:UniProtID
|
Q05513
|
|
gptkbp:bfsParent
|
gptkb:PKC
|
|
gptkbp:bfsLayer
|
6
|