|
gptkbp:instanceOf
|
gptkb:protein
gptkb:enzyme
|
|
gptkbp:activatedBy
|
phorbol esters
diacylglycerol
|
|
gptkbp:alternativeName
|
PKCε
protein kinase C epsilon type
|
|
gptkbp:associatedWith
|
gptkb:Alzheimer's_disease
gptkb:cancer
gptkb:cardiovascular_disease
|
|
gptkbp:cofactor
|
phospholipids
|
|
gptkbp:doesNotRequireCofactor
|
calcium
|
|
gptkbp:domain
|
gptkb:C1_domain
kinase domain
C2-like domain
|
|
gptkbp:encodedBy
|
PRKCE gene
|
|
gptkbp:enzymeCommissionNumber
|
2.7.11.13
|
|
gptkbp:expressedIn
|
gptkb:cancer
gptkb:skeletal_muscle
brain
heart
liver
|
|
gptkbp:familyMember
|
gptkb:protein_kinase_C_family
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
PKC epsilon
|
|
gptkbp:inhibitedBy
|
gptkb:chelerythrine
calphostin C
rottlerin
|
|
gptkbp:involvedIn
|
cell proliferation
signal transduction
cancer progression
apoptosis regulation
|
|
gptkbp:locatedOnChromosome
|
chromosome 2p21
|
|
gptkbp:molecularWeight
|
approx. 83 kDa
|
|
gptkbp:orthologIn
|
gptkb:mouse
gptkb:zebrafish
right
|
|
gptkbp:phosphorylates
|
gptkb:Akt
gptkb:STAT3
gptkb:GAP-43
gptkb:NF-κB
MARCKS protein
|
|
gptkbp:regulates
|
cell survival
cell migration
immune response
neurite outgrowth
cardiac function
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
gptkb:plasma_membrane
|
|
gptkbp:UniProtID
|
Q02156
|
|
gptkbp:bfsParent
|
gptkb:PKC
|
|
gptkbp:bfsLayer
|
6
|