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gptkbp:instanceOf
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gptkb:protein
|
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gptkbp:alternativeName
|
Protein kinase C epsilon type
nPKC-epsilon
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gptkbp:associatedWith
|
gptkb:cancer
gptkb:cardiovascular_disease
neurological disorders
|
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gptkbp:biologicalProcess
|
cell proliferation
signal transduction
apoptosis regulation
protein serine/threonine kinase activity
GO:0004674 (protein serine/threonine kinase activity)
GO:0007165 (signal transduction)
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gptkbp:cellularComponent
|
gptkb:cell_membrane
gptkb:cytoplasm
GO:0005737 (cytoplasm)
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gptkbp:cofactor
|
lipoprotein
diacylglycerol
calcium-independent
|
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gptkbp:Entrez_Gene_ID
|
gptkb:ENSP00000361789
5581
|
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gptkbp:enzymeClassification
|
EC 2.7.11.13
|
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gptkbp:family
|
gptkb:protein_kinase_C_family
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gptkbp:gene
|
gptkb:PRKCE
|
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gptkbp:HGNC_ID
|
9401
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Q02156 (PKC epsilon)
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gptkbp:InterPro
|
IPR000719 (Protein kinase C, conserved site)
|
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gptkbp:involves
|
gptkb:MAPK_signaling_pathway
PKC signaling pathway
|
|
gptkbp:KEGGID
|
hsa:5581
|
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gptkbp:length
|
737
|
|
gptkbp:locatedOnChromosome
|
chromosome 2p21
|
|
gptkbp:molecularWeight
|
83 kDa
|
|
gptkbp:OMIM
|
176980
|
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gptkbp:organism
|
gptkb:Homo_sapiens
|
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gptkbp:orthologInMouse
|
P09216
P09217
|
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gptkbp:PDB
|
2I0E
|
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gptkbp:phosphorylates
|
proteins involved in cell signaling
|
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gptkbp:postTranslationalModification
|
phosphorylation
autophosphorylation
|
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gptkbp:proteinFamily
|
PF00100 (Protein kinase domain)
|
|
gptkbp:Reactome
|
R-HSA-111465
|
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gptkbp:RefSeq
|
NP_005391.2
|
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gptkbp:reviewedBy
|
gptkb:UniProtKB/Swiss-Prot
|
|
gptkbp:subfamily
|
novel PKC (nPKC)
|
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gptkbp:subunit
|
monomer
forms complexes with other proteins
|
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gptkbp:tissue_specificity
|
widely expressed
|
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gptkbp:UniProtID
|
Q02156
|
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gptkbp:bfsParent
|
gptkb:PKC
|
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gptkbp:bfsLayer
|
6
|