|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:PRKCA
PKC-alpha
Protein kinase C, alpha type
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:cardiovascular_disease
|
|
gptkbp:biologicalProcess
|
apoptosis
cell differentiation
cell proliferation
protein kinase activity
|
|
gptkbp:cofactor
|
calcium
lipoprotein
diacylglycerol
|
|
gptkbp:discoveredIn
|
1987
|
|
gptkbp:Entrez_Gene_ID
|
5578
ENSG00000154229
|
|
gptkbp:enzymeClassification
|
EC 2.7.11.13
|
|
gptkbp:fullName
|
gptkb:Protein_kinase_C_alpha_type
|
|
gptkbp:function
|
gptkb:Signal_transduction
Serine/threonine-protein kinase activity
|
|
gptkbp:gene
|
gptkb:PRKCA
|
|
gptkbp:HGNC_ID
|
HGNC:9393
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
P17252 (PKC alpha)
|
|
gptkbp:KEGGID
|
hsa:5578
|
|
gptkbp:length
|
672 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:17q24
|
|
gptkbp:location
|
gptkb:nucleus
gptkb:cytoplasm
gptkb:plasma_membrane
|
|
gptkbp:molecularWeight
|
80 kDa
|
|
gptkbp:OMIM
|
176960
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:pathway
|
gptkb:MAPK_signaling_pathway
gptkb:Wnt_signaling_pathway
|
|
gptkbp:PDB
|
3iw4
4ra4
4ra5
|
|
gptkbp:phosphorylates
|
gptkb:MARCKS
GAP43
|
|
gptkbp:postTranslationalModification
|
phosphorylation
ubiquitination
myristoylation
|
|
gptkbp:Reactome
|
R-HSA-111465
|
|
gptkbp:RefSeq
|
NP_002730.2
|
|
gptkbp:reviewedBy
|
gptkb:UniProtKB/Swiss-Prot
|
|
gptkbp:subunit
|
monomer
forms complexes with other proteins
|
|
gptkbp:tissue_specificity
|
ubiquitous
|
|
gptkbp:UniProtID
|
P17252
|
|
gptkbp:bfsParent
|
gptkb:PKC
|
|
gptkbp:bfsLayer
|
6
|