|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alternativeName
|
PKC-iota
PRKCI_HUMAN
aPKC-iota
nPKC-iota
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:glioblastoma
pancreatic cancer
|
|
gptkbp:biologicalProcess
|
cell differentiation
cell survival
signal transduction
cell migration
epithelial cell polarity
ATP binding
protein kinase activity
tumorigenesis
protein binding
|
|
gptkbp:discovered_year
|
1994
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000163558
5584
|
|
gptkbp:expressedIn
|
gptkb:cancer
gptkb:testis
brain
pancreas
epithelial cells
|
|
gptkbp:fullName
|
Protein kinase C iota type
|
|
gptkbp:function
|
gptkb:NF-kappaB_signaling_pathway
serine/threonine-protein kinase activity
apoptosis regulation
cell proliferation regulation
cell polarity regulation
|
|
gptkbp:GO_term
|
gptkb:GO:0004674
GO:0005524
GO:0006468
GO:0030010
GO:0042981
|
|
gptkbp:HGNC_ID
|
HGNC:9400
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
PRKCI
|
|
gptkbp:interactsWith
|
gptkb:AKT1
gptkb:GSK3B
gptkb:CDC42
gptkb:NF-kappaB
gptkb:PAR-3
gptkb:PAR-6
Lgl
PARD3
PARD6B
PKC-zeta
|
|
gptkbp:locatedOnChromosome
|
3
3q26.2
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Prkci
|
|
gptkbp:proteinFamily
|
gptkb:protein_kinase_C_family
atypical protein kinase C subfamily
|
|
gptkbp:UniProtID
|
P41743
|
|
gptkbp:bfsParent
|
gptkb:PKC
|
|
gptkbp:bfsLayer
|
6
|