Inherited Cancer Syndromes

URI: https://gptkb.org/entity/Inherited_Cancer_Syndromes

GPTKB entity

Statements (86)

Predicate	Object
gptkbp:instanceOf	medical condition Genetic disorder
gptkbp:associatedWith	Increased cancer risk
gptkbp:causedBy	Germline mutations
gptkbp:diagnosedBy	Genetic testing
gptkbp:example	gptkb:PTEN_hamartoma_tumor_syndrome gptkb:Familial_adenomatous_polyposis gptkb:Werner_syndrome gptkb:Bloom_syndrome gptkb:Fanconi_anemia gptkb:Neurofibromatosis_type_2 gptkb:Carney_complex gptkb:Birt-Hogg-Dubé_syndrome gptkb:Li-Fraumeni_syndrome gptkb:Lynch_syndrome gptkb:Neurofibromatosis_type_1 gptkb:Ataxia-telangiectasia gptkb:Hereditary_breast_and_ovarian_cancer_syndrome gptkb:Hereditary_diffuse_gastric_cancer gptkb:Hereditary_leiomyomatosis_and_renal_cell_cancer gptkb:Hereditary_nonpolyposis_colorectal_cancer gptkb:Hereditary_papillary_renal_carcinoma gptkb:Hereditary_paraganglioma-pheochromocytoma_syndrome gptkb:Juvenile_polyposis_syndrome gptkb:Muir-Torre_syndrome gptkb:Multiple_endocrine_neoplasia gptkb:Retinoblastoma gptkb:Tuberous_sclerosis gptkb:Von_Hippel-Lindau_disease gptkb:Xeroderma_pigmentosum gptkb:Cowden_syndrome gptkb:Turcot_syndrome gptkb:Gorlin_syndrome gptkb:Peutz-Jeghers_syndrome gptkb:DICER1_syndrome
https://www.w3.org/2000/01/rdf-schema#label	Inherited Cancer Syndromes
gptkbp:inheritance	Autosomal dominant Autosomal recessive
gptkbp:managedBy	Surveillance Chemoprevention Genetic counseling Risk-reducing surgery
gptkbp:riskFactor	gptkb:Wilms_tumor gptkb:cancer gptkb:Endometrial_cancer gptkb:Melanoma gptkb:Medullary_thyroid_carcinoma gptkb:Colorectal_cancer gptkb:Pancreatic_cancer gptkb:Adrenocortical_carcinoma gptkb:Angiosarcoma gptkb:Bone_cancer gptkb:Chondrosarcoma gptkb:Eye_cancer gptkb:Gastrointestinal_stromal_tumors gptkb:Germ_cell_tumors gptkb:Hepatoblastoma gptkb:Osteosarcoma gptkb:Paraganglioma gptkb:Parathyroid_tumors gptkb:Pituitary_tumors gptkb:Renal_cancer gptkb:Retinoblastoma gptkb:Small_intestine_cancer gptkb:Soft_tissue_sarcoma gptkb:Thymic_tumors gptkb:Bladder_cancer gptkb:Gastric_cancer gptkb:rhabdomyosarcoma gptkb:Pheochromocytoma Lymphoma Lung cancer Leukemia Meningioma Schwannoma Oral cancer Brain tumors Prostate cancer Esophageal cancer Skin cancer Breast cancer Ovarian cancer Testicular cancer Liver cancer
gptkbp:bfsParent	gptkb:Shirley_Hodgson
gptkbp:bfsLayer	6