|
gptkbp:instanceOf
|
gptkb:disease
gptkb:malignant_bone_tumor
|
|
gptkbp:5YearSurvivalRate
|
60-70% (localized disease)
|
|
gptkbp:affects
|
gptkb:dog
humans
cats
|
|
gptkbp:associatedWith
|
radiation exposure
|
|
gptkbp:canBePrimary
|
yes
|
|
gptkbp:canBeSecondary
|
yes
|
|
gptkbp:canMetastasizeTo
|
lungs
other bones
|
|
gptkbp:commonIn
|
adolescents
young adults
males
|
|
gptkbp:diagnosedBy
|
gptkb:X-rays
gptkb:CT_scan
MRI
biopsy
|
|
gptkbp:firstDescribed
|
1805
|
|
gptkbp:histology
|
malignant osteoid production
|
|
gptkbp:ICD-10_code
|
C40
C41
|
|
gptkbp:incidence
|
2-3 per million per year (children and adolescents)
|
|
gptkbp:MeSH_ID
|
D012516
|
|
gptkbp:occurredIn
|
any bone
|
|
gptkbp:OMIM
|
259500
|
|
gptkbp:originatedIn
|
gptkb:bone
osteoblast
|
|
gptkbp:prognosis
|
variable
|
|
gptkbp:rareIn
|
adults over 40
|
|
gptkbp:riskFactor
|
gptkb:Li-Fraumeni_syndrome
gptkb:Paget's_disease
hereditary retinoblastoma
|
|
gptkbp:subspecies
|
conventional osteosarcoma
high-grade surface osteosarcoma
parosteal osteosarcoma
periosteal osteosarcoma
small cell osteosarcoma
telangiectatic osteosarcoma
|
|
gptkbp:symptom
|
bone pain
swelling
pathological fracture
|
|
gptkbp:treatment
|
gptkb:radiation_therapy
surgery
chemotherapy
|
|
gptkbp:website
|
proximal humerus
distal femur
proximal tibia
|
|
gptkbp:bfsParent
|
gptkb:Inherited_Cancer_Syndromes
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Osteosarcoma
|