Endometrial cancer

GPTKB entity

Statements (59)
Predicate Object
gptkbp:instanceOf gptkb:cancer
Gynecological cancer
gptkbp:affects gptkb:Uterus
Endometrium
gptkbp:canBeMalignant Yes
gptkbp:canBeSporadic Yes
gptkbp:canMetastasizeTo gptkb:bone
Lungs
Liver
Lymph nodes
gptkbp:diagnosedBy Dilation and curettage
Endometrial biopsy
Transvaginal ultrasound
gptkbp:firstDescribed 19th century
gptkbp:hereditary Yes
https://www.w3.org/2000/01/rdf-schema#label Endometrial cancer
gptkbp:ICD-10_code gptkb:C54.1
gptkbp:incidenceInUS ~66,000 new cases per year (2023)
gptkbp:isHormoneDependent Often
gptkbp:isMostCommonGynecologicalCancerIn gptkb:United_States
gptkbp:medianAge 60 years
gptkbp:mortalityInUS ~13,000 deaths per year (2023)
gptkbp:mostCommonType gptkb:Endometrioid_adenocarcinoma
gptkbp:otherTypes gptkb:Clear_cell_carcinoma
gptkb:Carcinosarcoma
gptkb:Serous_carcinoma
gptkbp:prevention physical activity
Weight management
Oral contraceptive use
gptkbp:prognosis Histological grade
Lymph node involvement
Stage at diagnosis
Patient age
gptkbp:rareIn Women under 40
gptkbp:riskFactor gptkb:Lynch_syndrome
gptkb:Polycystic_ovary_syndrome
Diabetes
Obesity
Hypertension
Early menarche
Estrogen exposure
Late menopause
Nulliparity
Tamoxifen use
gptkbp:screeningRecommendedFor Women with Lynch syndrome
gptkbp:stageName gptkb:FIGO_staging
gptkb:AJCC_staging
gptkbp:symptom Weight loss
Abnormal uterine bleeding
Pelvic pain
Postmenopausal bleeding
gptkbp:treatment radiation therapy
Surgery
Chemotherapy
Hormone therapy
Hysterectomy
gptkbp:bfsParent gptkb:Clear_cell_carcinoma
gptkb:Womb
gptkbp:bfsLayer 6