Hereditary breast and ovarian cancer syndrome
GPTKB entity
Statements (22)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
genetic disorder
|
| gptkbp:alsoKnownAs |
gptkb:HBOC
|
| gptkbp:associatedWith |
BRCA1 gene mutation
BRCA2 gene mutation |
| gptkbp:diagnosedBy |
genetic testing
|
| gptkbp:firstDescribed |
1990s
|
| https://www.w3.org/2000/01/rdf-schema#label |
Hereditary breast and ovarian cancer syndrome
|
| gptkbp:inheritsFrom |
autosomal dominant manner
|
| gptkbp:managedBy |
risk-reducing surgery
chemoprevention increased surveillance |
| gptkbp:OMIM |
604370
|
| gptkbp:prevalence |
about 1 in 400 people
|
| gptkbp:relevantPopulation |
Ashkenazi Jewish descent
|
| gptkbp:riskFactor |
gptkb:cancer
pancreatic cancer prostate cancer |
| gptkbp:symptom |
early-onset breast cancer
male breast cancer multiple family members with breast or ovarian cancer |
| gptkbp:bfsParent |
gptkb:Inherited_Cancer_Syndromes
|
| gptkbp:bfsLayer |
7
|