|
gptkbp:instanceOf
|
gptkb:cancer
gptkb:disease
|
|
gptkbp:affects
|
adrenal cortex
|
|
gptkbp:alternativeName
|
gptkb:ACC
adrenal cortical carcinoma
|
|
gptkbp:associatedWith
|
gptkb:TP53_mutation
IGF2 overexpression
|
|
gptkbp:firstDescribed
|
gptkb:Arnold
1865
|
|
gptkbp:hasDiagnosticMethod
|
gptkb:CT_scan
MRI
biopsy
hormonal evaluation
|
|
gptkbp:hasMetastasisSite
|
gptkb:cancer
gptkb:bone
liver
lymph nodes
|
|
gptkbp:hasOrphanetID
|
ORPHA:328
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Adrenocortical carcinoma
|
|
gptkbp:ICD-10_code
|
C74
|
|
gptkbp:incidence
|
1-2 per million per year
|
|
gptkbp:medianAge
|
40-50 years
|
|
gptkbp:MeSH_ID
|
D000309
|
|
gptkbp:mortalityRate
|
high
|
|
gptkbp:originatedIn
|
adrenocortical cells
|
|
gptkbp:prevalence
|
rare
|
|
gptkbp:prognosis
|
poor
tumor stage
Ki-67 index
hormonal activity
resectability
|
|
gptkbp:riskFactor
|
gptkb:Li-Fraumeni_syndrome
gptkb:Multiple_endocrine_neoplasia_type_1
gptkb:Beckwith-Wiedemann_syndrome
family history
|
|
gptkbp:stageName
|
gptkb:AJCC
gptkb:ENSAT
|
|
gptkbp:symptom
|
gptkb:Cushing's_syndrome
abdominal pain
hypertension
weight loss
virilization
hormonal imbalance
|
|
gptkbp:treatment
|
surgery
radiation therapy
chemotherapy
mitotane
|
|
gptkbp:bfsParent
|
gptkb:Inherited_Cancer_Syndromes
|
|
gptkbp:bfsLayer
|
7
|