Multiple endocrine neoplasia
GPTKB entity
Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
genetic disorder
syndrome |
| gptkbp:abbreviation |
gptkb:MEN
|
| gptkbp:affects |
endocrine system
|
| gptkbp:associatedWith |
gptkb:pheochromocytoma
gptkb:medullary_thyroid_carcinoma parathyroid tumors pituitary tumors pancreatic tumors |
| gptkbp:field |
endocrinology
|
| gptkbp:firstDescribed |
1954
Paul Wermer |
| gptkbp:hasType |
gptkb:MEN2
gptkb:MEN1 MEN3 |
| https://www.w3.org/2000/01/rdf-schema#label |
Multiple endocrine neoplasia
|
| gptkbp:ICD-10_code |
E31.2
|
| gptkbp:inheritance |
autosomal dominant
|
| gptkbp:mutationAssociatedWith |
gptkb:MEN1_gene
gptkb:RET_gene |
| gptkbp:OMIM |
131100
|
| gptkbp:prevalence |
rare
|
| gptkbp:riskFactor |
increased cancer risk
|
| gptkbp:subspecies |
gptkb:MEN2A
gptkb:MEN2B gptkb:MEN1 |
| gptkbp:symptom |
hormonal imbalances
tumors of endocrine glands |
| gptkbp:treatment |
surgery
genetic counseling hormone therapy |
| gptkbp:bfsParent |
gptkb:cancer_predisposition_syndrome
|
| gptkbp:bfsLayer |
6
|