Statements (58)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:Genetics
|
| gptkbp:associated_with |
gptkb:MSH2_gene_mutation
gptkb:MSH6_gene_mutation gptkb:educational_resources research studies clinical trials mental health support awareness campaigns patient advocacy groups exercise guidelines legal considerations support networks dietary recommendations lifestyle modifications financial assistance programs treatment protocols insurance coverage issues long-term follow-up care cancer registries screening guidelines Lynch syndrome families defective DNA mismatch repair survivorship plans tumor microsatellite instability MLH1 gene mutation PMS2 gene mutation |
| gptkbp:cause |
gptkb:Oncology
ovarian cancer endometrial cancer stomach cancer small intestine cancer urinary tract cancer |
| gptkbp:diagnosis |
genetic testing
|
| gptkbp:first_described_by |
gptkb:Henry_T._Lynch
|
| gptkbp:genetic_counseling_recommended_for |
affected individuals
at-risk relatives |
| https://www.w3.org/2000/01/rdf-schema#label |
Lynch syndrome
|
| gptkbp:investment |
gptkb:adrenal_cancer
gptkb:bile_duct_cancer gptkb:Oncology gptkb:pancreatic_cancer brain cancer neuroendocrine tumors |
| gptkbp:known_as |
gptkb:hereditary_nonpolyposis_colorectal_cancer_(HNPCC)
|
| gptkbp:managed_by |
oncologists
surgeons genetic counselors |
| gptkbp:prevalence |
1 in 300 to 1 in 400 individuals
|
| gptkbp:risk_factor |
multiple cancers
|
| gptkbp:screenings |
gptkb:family
|
| gptkbp:symptoms |
increased cancer risk
family history of cancer |
| gptkbp:treatment |
gptkb:immunotherapy
gptkb:surgery surveillance chemotherapy |
| gptkbp:bfsParent |
gptkb:Ovarian_Cancer
|
| gptkbp:bfsLayer |
5
|