|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alias
|
gptkb:C-H-RAS
gptkb:HRAS1
gptkb:v-Ha-ras_Harvey_rat_sarcoma_viral_oncogene_homolog
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:discoveredBy
|
gptkb:Harold_E._Varmus
gptkb:J._Michael_Bishop
|
|
gptkbp:encodes
|
gptkb:GTPase_HRas
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000174775
3265
|
|
gptkbp:expressedIn
|
many tissues
|
|
gptkbp:fullName
|
gptkb:Harvey_rat_sarcoma_viral_oncogene_homolog
|
|
gptkbp:function
|
signal transduction
regulation of cell division
regulation of cell growth
|
|
gptkbp:geneType
|
tumor suppressor
|
|
gptkbp:hasClinicalTest
|
HRAS mutation analysis
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
H-ras
|
|
gptkbp:interactsWith
|
gptkb:GAPs
gptkb:PI3K
gptkb:RAF1
gptkb:SOS1
|
|
gptkbp:length
|
189
|
|
gptkbp:locatedOnChromosome
|
gptkb:11p15.5
chromosome 11
|
|
gptkbp:memberOf
|
gptkb:RAS_gene_family
|
|
gptkbp:molecularWeight
|
21 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:cancer
gptkb:Costello_syndrome
gptkb:head_and_neck_squamous_cell_carcinoma
bladder cancer
|
|
gptkbp:OMIM
|
190020
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:HRAS_(mouse)
|
|
gptkbp:PDB
|
gptkb:5P21
gptkb:1QRA
3K8Y
|
|
gptkbp:postTranslationalModification
|
farnesylation
palmitoylation
|
|
gptkbp:proteinFamily
|
small molecule
|
|
gptkbp:relatedTo
|
gptkb:K-ras
gptkb:N-ras
|
|
gptkbp:subcellularLocation
|
gptkb:endoplasmic_reticulum
gptkb:Golgi_apparatus
gptkb:plasma_membrane
|
|
gptkbp:symbol
|
gptkb:HRAS
|
|
gptkbp:UniProtID
|
gptkb:P01112
|
|
gptkbp:bfsParent
|
gptkb:N-ras
|
|
gptkbp:bfsLayer
|
6
|