Statements (26)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alsoKnownAs |
gptkb:Philadelphia_chromosome
|
| gptkbp:associatedWith |
gptkb:chronic_myeloid_leukemia
leukemia |
| gptkbp:category |
tumor suppressor
biomarker molecular target |
| gptkbp:cause |
uncontrolled cell division
|
| gptkbp:discoveredBy |
gptkb:Janet_Rowley
|
| gptkbp:discoveredIn |
1973
|
| gptkbp:encodes |
constitutively active tyrosine kinase
|
| gptkbp:formedBy |
translocation between chromosome 9 and chromosome 22
|
| https://www.w3.org/2000/01/rdf-schema#label |
BCR-ABL
|
| gptkbp:locatedOn |
gptkb:Philadelphia_chromosome
|
| gptkbp:product |
gptkb:p190_BCR-ABL
gptkb:p210_BCR-ABL gptkb:p230_BCR-ABL |
| gptkbp:result |
gptkb:t(9;22)(q34;q11)_translocation
|
| gptkbp:target |
gptkb:bosutinib
gptkb:dasatinib gptkb:ponatinib gptkb:imatinib gptkb:nilotinib |
| gptkbp:usedAs |
diagnostic marker for CML
|
| gptkbp:bfsParent |
gptkb:Tasigna
|
| gptkbp:bfsLayer |
5
|