Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:ASH
gptkb:GRB2 adapter protein GRB2 |
| gptkbp:discoveredBy |
gptkb:Tony_Pawson
|
| gptkbp:domain |
SH2 domain
SH3 domain |
| gptkbp:fullName |
gptkb:Growth_factor_receptor-bound_protein_2
|
| gptkbp:function |
adaptor protein in signal transduction
|
| gptkbp:gene |
gptkb:GRB2
|
| https://www.w3.org/2000/01/rdf-schema#label |
Grb-2
|
| gptkbp:interactsWith |
gptkb:EGFR
gptkb:SOS1 gptkb:Shc |
| gptkbp:involvedIn |
gptkb:RAS/MAPK_signaling_pathway
cell differentiation cell growth regulation |
| gptkbp:locale |
gptkb:cytoplasm
gptkb:plasma_membrane |
| gptkbp:locatedOnChromosome |
gptkb:17q25
|
| gptkbp:molecularWeight |
~25 kDa
|
| gptkbp:OMIM |
108355
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:PDB |
gptkb:1GRI
|
| gptkbp:phosphorylates |
tyrosine residues
|
| gptkbp:UniProtID |
gptkb:P62993
|
| gptkbp:bfsParent |
gptkb:GRB2
|
| gptkbp:bfsLayer |
6
|