|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:GAB1_scaffolding_protein
gptkb:GRB2-associated-binding_protein_1
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:Noonan_syndrome
|
|
gptkbp:discoveredIn
|
1996
|
|
gptkbp:encodes
|
gptkb:GRB2-associated-binding_protein_1
|
|
gptkbp:Entrez_Gene_ID
|
2549
ENSG00000109919
|
|
gptkbp:expressedIn
|
various tissues
|
|
gptkbp:fullName
|
gptkb:GRB2-associated_binding_protein_1
|
|
gptkbp:function
|
scaffolding protein in signal transduction
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
4065
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
GAB1
|
|
gptkbp:interactsWith
|
gptkb:EGFR
gptkb:PIK3R1
gptkb:SHC1
gptkb:SHP2
gptkb:GRB2
gptkb:MET
|
|
gptkbp:involvedIn
|
gptkb:MAPK_signaling_pathway
gptkb:PI3K-Akt_signaling_pathway
|
|
gptkbp:length
|
694 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_4
4q31.1
|
|
gptkbp:molecularWeight
|
77 kDa
|
|
gptkbp:OMIM
|
604360
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Gab1
|
|
gptkbp:phosphorylates
|
tyrosine residues
|
|
gptkbp:regulates
|
cell differentiation
cell survival
cell growth
|
|
gptkbp:UniProtID
|
Q13480
|
|
gptkbp:bfsParent
|
gptkb:GRB2
gptkb:KEGG:_hsa04014
|
|
gptkbp:bfsLayer
|
6
|