gptkbp:instanceOf
|
non-coding RNA
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:cardiovascular_disease
atherosclerosis
smooth muscle cell phenotype
|
gptkbp:biogenesis
|
Dicer-dependent
|
gptkbp:databaseEntry
|
gptkb:Ensembl:ENSG00000207949
gptkb:Entrez_Gene:406938
gptkb:HGNC:31588
gptkb:miRBase:MI0000461
|
gptkbp:downregulatedIn
|
gptkb:SMAD3
gptkb:FSCN1
gptkb:Fascin-1
gptkb:JAM-A
gptkb:MUC1
gptkb:KLF4
gptkb:ADAM17
gptkb:c-Myc
gptkb:N-Ras
gptkb:OCT4
gptkb:SOX2
gptkb:IGF1R
gptkb:IRS-1
|
gptkbp:expressedIn
|
vascular smooth muscle cells
breast tissue
lung tissue
colorectal tissue
prostate tissue
|
gptkbp:firstDescribed
|
2005
|
gptkbp:foundIn
|
gptkb:Mus_musculus
gptkb:Homo_sapiens
|
https://www.w3.org/2000/01/rdf-schema#label
|
miR-145
|
gptkbp:involvedIn
|
cell differentiation
tumor suppression
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_5_(human)
|
gptkbp:regulates
|
gene expression
|
gptkbp:role
|
tumor suppressor
regulator of apoptosis
regulator of cell migration
regulator of cell proliferation
regulator of cytoskeleton organization
regulator of stem cell pluripotency
|
gptkbp:sequence
|
non-coding RNA
|
gptkbp:target
|
multiple mRNAs
|
gptkbp:bfsParent
|
gptkb:p53
|
gptkbp:bfsLayer
|
6
|