miR-145

GPTKB entity

Statements (46)
Predicate Object
gptkbp:instanceOf non-coding RNA
gptkbp:associatedWith gptkb:cancer
gptkb:cardiovascular_disease
atherosclerosis
smooth muscle cell phenotype
gptkbp:biogenesis Dicer-dependent
gptkbp:databaseEntry gptkb:Ensembl:ENSG00000207949
gptkb:Entrez_Gene:406938
gptkb:HGNC:31588
gptkb:miRBase:MI0000461
gptkbp:downregulatedIn gptkb:SMAD3
gptkb:FSCN1
gptkb:Fascin-1
gptkb:JAM-A
gptkb:MUC1
gptkb:KLF4
gptkb:ADAM17
gptkb:c-Myc
gptkb:N-Ras
gptkb:OCT4
gptkb:SOX2
gptkb:IGF1R
gptkb:IRS-1
gptkbp:expressedIn vascular smooth muscle cells
breast tissue
lung tissue
colorectal tissue
prostate tissue
gptkbp:firstDescribed 2005
gptkbp:foundIn gptkb:Mus_musculus
gptkb:Homo_sapiens
https://www.w3.org/2000/01/rdf-schema#label miR-145
gptkbp:involvedIn cell differentiation
tumor suppression
gptkbp:locatedOnChromosome gptkb:chromosome_5_(human)
gptkbp:regulates gene expression
gptkbp:role tumor suppressor
regulator of apoptosis
regulator of cell migration
regulator of cell proliferation
regulator of cytoskeleton organization
regulator of stem cell pluripotency
gptkbp:sequence non-coding RNA
gptkbp:target multiple mRNAs
gptkbp:bfsParent gptkb:p53
gptkbp:bfsLayer 6