|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alias
|
gptkb:NRAS
gptkb:Neuroblastoma_RAS_viral_oncogene_homolog
gptkb:CMMTC
|
|
gptkbp:discoveredBy
|
gptkb:Edward_Scolnick
|
|
gptkbp:discoveredIn
|
1983
|
|
gptkbp:encodedBy
|
gptkb:NRAS_gene
|
|
gptkbp:Entrez_Gene_ID
|
4893
|
|
gptkbp:foundIn
|
gptkb:Homo_sapiens
|
|
gptkbp:function
|
signal transduction
regulation of cell differentiation
regulation of cell proliferation
|
|
gptkbp:hasBiologicalActivity
|
guanine nucleotide exchange factor
|
|
gptkbp:HGNC_ID
|
7989
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
N-Ras
|
|
gptkbp:interactsWith
|
gptkb:PI3K
gptkb:GRB2
gptkb:RAF1
gptkb:SOS1
|
|
gptkbp:locatedOnChromosome
|
chromosome 1
|
|
gptkbp:memberOf
|
gptkb:small_GTPase_family
gptkb:Ras_subfamily
|
|
gptkbp:mutationAssociatedWith
|
gptkb:cancer
gptkb:acute_myeloid_leukemia
colorectal cancer
melanoma
hematologic malignancies
|
|
gptkbp:OMIM
|
164790
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Rattus_norvegicus
|
|
gptkbp:postTranslationalModification
|
farnesylation
palmitoylation
|
|
gptkbp:subcellularLocation
|
gptkb:Golgi_apparatus
gptkb:plasma_membrane
|
|
gptkbp:UniProtID
|
gptkb:P01111
|
|
gptkbp:bfsParent
|
gptkb:Ras_protein
|
|
gptkbp:bfsLayer
|
6
|