|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:CD321
Junctional adhesion molecule 1
|
|
gptkbp:encodedBy
|
gptkb:F11R_gene
|
|
gptkbp:expressedIn
|
gptkb:leukocytes
platelets
endothelial cells
epithelial cells
|
|
gptkbp:foundIn
|
gptkb:human
gptkb:mouse
|
|
gptkbp:fullName
|
gptkb:Junctional_Adhesion_Molecule_A
|
|
gptkbp:function
|
cell adhesion
platelet aggregation
leukocyte transmigration
regulation of paracellular permeability
|
|
gptkbp:gene
|
F11R
|
|
gptkbp:GO
|
GO:0005911 (cell-cell junction)
|
|
gptkbp:interactsWith
|
gptkb:PAR-3
ZO-1
platelet F11 receptor
|
|
gptkbp:locatedOnChromosome
|
chromosome 1q21.1
|
|
gptkbp:location
|
tight junctions
|
|
gptkbp:molecularWeight
|
~32 kDa
|
|
gptkbp:PDB
|
1NBQ
|
|
gptkbp:significance
|
involved in inflammation
associated with atherosclerosis
implicated in cancer metastasis
|
|
gptkbp:structure
|
type I transmembrane glycoprotein
|
|
gptkbp:UniProtID
|
gptkb:Q9Y624
|
|
gptkbp:bfsParent
|
gptkb:reovirus
gptkb:miR-145
gptkb:CD321
gptkb:CD323
|
|
gptkbp:bfsLayer
|
8
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
JAM-A
|