JAM-A

GPTKB entity

Statements (32)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeName gptkb:CD321
Junctional adhesion molecule 1
gptkbp:encodedBy gptkb:F11R_gene
gptkbp:expressedIn gptkb:leukocytes
platelets
endothelial cells
epithelial cells
gptkbp:foundIn gptkb:human
gptkb:mouse
gptkbp:fullName gptkb:Junctional_Adhesion_Molecule_A
gptkbp:function cell adhesion
platelet aggregation
leukocyte transmigration
regulation of paracellular permeability
gptkbp:gene F11R
gptkbp:GO GO:0005911 (cell-cell junction)
https://www.w3.org/2000/01/rdf-schema#label JAM-A
gptkbp:interactsWith gptkb:PAR-3
ZO-1
platelet F11 receptor
gptkbp:locatedOnChromosome chromosome 1q21.1
gptkbp:location tight junctions
gptkbp:molecularWeight ~32 kDa
gptkbp:PDB 1NBQ
gptkbp:significance involved in inflammation
associated with atherosclerosis
implicated in cancer metastasis
gptkbp:structure type I transmembrane glycoprotein
gptkbp:UniProtID gptkb:Q9Y624
gptkbp:bfsParent gptkb:miR-145
gptkbp:bfsLayer 7