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gptkbp:instanceOf
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non-coding RNA
biological molecule
RNA molecule
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gptkbp:abbreviated_as
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gptkb:miRNA
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gptkbp:abbreviation
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gptkb:snRNA
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gptkbp:alternativeName
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long_non-coding_RNA
microRNA
small_nuclear_RNA
small_nucleolar_RNA
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gptkbp:binds
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messenger RNA
small nuclear ribonucleoproteins
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gptkbp:canBe
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biomarker
therapeutic target
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gptkbp:cause
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mRNA degradation
translation inhibition
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gptkbp:component
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gptkb:spliceosome
snoRNP complex
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gptkbp:discoveredBy
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gptkb:Victor_Ambros
gptkb:Rosalind_Lee
gptkb:Caenorhabditis_elegans
1993
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gptkbp:discoveredIn
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1960s
eukaryotes
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gptkbp:encodedBy
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microRNA genes
introns of host genes
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gptkbp:example
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gptkb:U1_snRNA
gptkb:U2_snRNA
gptkb:U4_snRNA
gptkb:U5_snRNA
gptkb:U6_snRNA
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gptkbp:firstDescribed
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gptkb:lin-4
1970s
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gptkbp:formsComplexWith
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gptkb:RNA-induced_silencing_complex
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gptkbp:foundIn
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nucleolus
eukaryotes
eukaryotic cell nucleus
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gptkbp:function
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RNA splicing
modification of other RNAs
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gptkbp:functions_in
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RNA silencing
post-transcriptional regulation
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gptkbp:guidanceSystem
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2'-O-methylation
pseudouridylation
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gptkbp:involvedIn
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rRNA processing
pre-mRNA processing
snRNA modification
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gptkbp:length
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about 22 nucleotides
100-300 nucleotides
60-300 nucleotides
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gptkbp:locatedOnChromosome
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gptkb:nucleus
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gptkbp:presentIn
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all eukaryotes
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gptkbp:processed_by
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gptkb:Drosha_enzyme
gptkb:Dicer_enzyme
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gptkbp:regulates
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gene expression
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gptkbp:relatedTo
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non-coding RNA
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gptkbp:role
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catalysis of splicing reactions
recognition of splice sites
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gptkbp:studiedBy
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cancer research
developmental biology
neurobiology
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gptkbp:type
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gptkb:C/D_box_snoRNA
gptkb:H/ACA_box_snoRNA
non-coding RNA
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gptkbp:bfsParent
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gptkb:gene
gptkb:RNA_interference
gptkb:MRNA
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gptkbp:bfsLayer
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5
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