constitutive androstane receptor
GPTKB entity
Statements (62)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:physicist
|
| gptkbp:analyzes |
metabolic syndrome
drug interactions |
| gptkbp:associated_with |
drug metabolism
|
| gptkbp:can_create |
coactivators
|
| gptkbp:community |
cytochrome P450 enzymes
|
| gptkbp:established |
gptkb:physicist
certain compounds |
| gptkbp:function |
regulates gene expression
|
| gptkbp:game_components |
nuclear signaling pathways
|
| gptkbp:has_role |
endocrine signaling
|
| https://www.w3.org/2000/01/rdf-schema#label |
constitutive androstane receptor
|
| gptkbp:influences |
bile acid synthesis
|
| gptkbp:interacts_with |
other nuclear receptors
|
| gptkbp:is_associated_with |
liver diseases
chronic diseases insulin resistance chronic inflammation endocrine disruptors |
| gptkbp:is_involved_in |
cell differentiation
cell proliferation cellular homeostasis glucose metabolism immune response stress response cell signaling pathways carcinogenesis hormonal regulation neurotransmitter regulation metabolic adaptation cellular signaling. hormone signaling xenobiotic response |
| gptkbp:is_linked_to |
age-related diseases
reproductive health metabolic disorders obesity cardiovascular health environmental toxins |
| gptkbp:is_part_of |
nuclear receptor superfamily
|
| gptkbp:is_represented_in |
gptkb:skincare_product
liver intestine |
| gptkbp:is_studied_in |
toxicology
toxicogenomics |
| gptkbp:is_tested_for |
liver function
|
| gptkbp:key_people |
metabolic pathways
|
| gptkbp:location |
gptkb:physicist
|
| gptkbp:products |
androgens
|
| gptkbp:promoter |
N R1 I3
|
| gptkbp:regulates |
lipid metabolism
post-translational modifications cholesterol homeostasis |
| gptkbp:research |
drug efficacy
cancer therapy health outcomes metabolic regulation |
| gptkbp:research_focus |
endocrinology
pharmacogenomics |
| gptkbp:targets |
gptkb:physicist
gptkb:drug small molecule drugs |