Statements (38)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:encodes |
gptkb:CYP3A_enzymes
|
| gptkbp:expressedIn |
liver
intestine |
| gptkbp:foundIn |
humans
other mammals |
| gptkbp:function |
drug metabolism
steroid metabolism xenobiotic metabolism |
| gptkbp:HGNC_ID |
2622
|
| https://www.w3.org/2000/01/rdf-schema#label |
CYP3A
|
| gptkbp:includes |
gptkb:CYP3A5
gptkb:CYP3A4 gptkb:CYP3A43 gptkb:CYP3A7 |
| gptkbp:inducedBy |
gptkb:rifampicin
gptkb:carbamazepine |
| gptkbp:inhibitedBy |
gptkb:milk
gptkb:ketoconazole |
| gptkbp:locatedOnChromosome |
gptkb:chromosome_7q21.1
|
| gptkbp:OMIM |
124010
|
| gptkbp:partOf |
gptkb:cytochrome_P450_superfamily
|
| gptkbp:regulates |
gptkb:constitutive_androstane_receptor
gptkb:pregnane_X_receptor |
| gptkbp:relatedTo |
pharmacogenomics
adverse drug reactions drug-drug interactions |
| gptkbp:substrate |
gptkb:cyclosporine
gptkb:erythromycin gptkb:midazolam testosterone |
| gptkbp:UniProtID |
gptkb:P08684_(CYP3A4)
gptkb:P24462_(CYP3A7) P20815 (CYP3A5) Q9HB55 (CYP3A43) |
| gptkbp:bfsParent |
gptkb:idelalisib
gptkb:CYP3A4 |
| gptkbp:bfsLayer |
5
|