|
gptkbp:instanceOf
|
antifungal medication
imidazole derivative
|
|
gptkbp:ATCCode
|
D01AC02
|
|
gptkbp:bioavailability
|
poor (topical)
|
|
gptkbp:brand
|
gptkb:Lotrimin
gptkb:Mycelex
gptkb:Canesten
|
|
gptkbp:CASNumber
|
23593-75-1
|
|
gptkbp:contraindication
|
hypersensitivity to clotrimazole
|
|
gptkbp:discoveredBy
|
gptkb:Bayer
|
|
gptkbp:discoveredIn
|
1969
|
|
gptkbp:drugClass
|
antifungal
|
|
gptkbp:eliminationHalfLife
|
2 hours (oral)
|
|
gptkbp:excretion
|
urine
bile
|
|
gptkbp:hasMolecularFormula
|
C22H17ClN2
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
clotrimazole
|
|
gptkbp:IUPACName
|
1-[(2-chlorophenyl)(diphenyl)methyl]-1H-imidazole
|
|
gptkbp:legalStatus
|
over-the-counter (OTC)
|
|
gptkbp:mechanismOfAction
|
inhibits ergosterol synthesis
|
|
gptkbp:meltingPoint
|
147°C
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:pregnancyCategory
|
A
C (US)
|
|
gptkbp:prescriptionStatus
|
OTC in many countries
|
|
gptkbp:PubChem_CID
|
2812
2710
|
|
gptkbp:routeOfAdministration
|
topical
vaginal
oral (lozenge)
|
|
gptkbp:sideEffect
|
itching
skin irritation
redness
blistering
|
|
gptkbp:solubility
|
practically insoluble in water
|
|
gptkbp:synonym
|
gptkb:clotrimazol
gptkb:clotrimazolum
Bay b 5097
|
|
gptkbp:UNII
|
G07GZ23Y0R
|
|
gptkbp:usedFor
|
treatment of fungal infections
treatment of athlete's foot
treatment of jock itch
treatment of ringworm
treatment of vaginal yeast infections
|
|
gptkbp:WHOModelListOfEssentialMedicines
|
included
|
|
gptkbp:bfsParent
|
gptkb:Candidiasis
|
|
gptkbp:bfsLayer
|
5
|