|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:ARVD
TGF-beta 3
FLJ16571
R-C-TGF
|
|
gptkbp:associatedWith
|
cleft palate
Marfan syndrome-like phenotype
|
|
gptkbp:component
|
extracellular region
|
|
gptkbp:discoveredBy
|
Derynck et al.
|
|
gptkbp:discoveredIn
|
1988
|
|
gptkbp:encodes
|
TGF-beta 3 protein
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000119699
7043
|
|
gptkbp:expressedIn
|
various tissues
|
|
gptkbp:fullName
|
transforming growth factor beta 3
|
|
gptkbp:function
|
wound healing
regulation of cell differentiation
immune system regulation
embryogenesis
regulation of cell growth
cytokine activity
|
|
gptkbp:GOProcess
|
signal transduction
cellular response to growth factor stimulus
|
|
gptkbp:HGNC_ID
|
HGNC:11768
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
TGFB3
|
|
gptkbp:interactsWith
|
gptkb:TGFBR2
gptkb:TGFBR1
gptkb:SMAD_proteins
|
|
gptkbp:length
|
412 amino acids
|
|
gptkbp:locatedOnChromosome
|
14q24
|
|
gptkbp:memberOf
|
gptkb:TGF-beta_superfamily
|
|
gptkbp:molecularWeight
|
47 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:arrhythmogenic_right_ventricular_dysplasia
|
|
gptkbp:OMIM
|
190230
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Tgfb3
|
|
gptkbp:pathway
|
gptkb:TGF-beta_signaling_pathway
|
|
gptkbp:proteinFamily
|
transforming growth factor beta family
|
|
gptkbp:regulates
|
apoptosis
cell migration
epithelial-mesenchymal transition
extracellular matrix production
|
|
gptkbp:UniProtID
|
P10600
|
|
gptkbp:bfsParent
|
gptkb:TGF-beta
|
|
gptkbp:bfsLayer
|
7
|