Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alias |
gptkb:TGF-beta
|
| gptkbp:associatedWith |
gptkb:cancer
gptkb:Marfan_syndrome gptkb:systemic_sclerosis fibrotic diseases |
| gptkbp:discoveredBy |
De Larco and Todaro
|
| gptkbp:discoveredIn |
1978
|
| gptkbp:Entrez_Gene_ID |
7040
|
| gptkbp:expressedIn |
many tissues
|
| gptkbp:fullName |
Transforming Growth Factor Beta
|
| gptkbp:function |
regulation of apoptosis
regulation of cell differentiation regulation of cell growth regulation of immune response |
| https://www.w3.org/2000/01/rdf-schema#label |
TGFB
|
| gptkbp:involvedIn |
wound healing
cancer progression fibrosis |
| gptkbp:locatedOnChromosome |
19q13.1
|
| gptkbp:molecularWeight |
25 kDa (dimer)
|
| gptkbp:orthologIn |
gptkb:TGFB1
gptkb:TGFB2 gptkb:TGFB3 |
| gptkbp:pathway |
gptkb:SMAD_pathway
|
| gptkbp:proteinFamily |
gptkb:TGF-beta_superfamily
|
| gptkbp:recipient |
gptkb:TGF-beta_receptor
|
| gptkbp:structure |
homodimer
|
| gptkbp:UniProtID |
P01137
|
| gptkbp:bfsParent |
gptkb:TGF-beta
|
| gptkbp:bfsLayer |
7
|