TGF-beta receptor type III

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein
gptkbp:alsoKnownAs	betaglycan
gptkbp:alternativeSplicing	yes
gptkbp:binds	gptkb:TGF-beta1 gptkb:TGF-beta2 gptkb:TGF-beta3
gptkbp:biologicalProcess	cell differentiation embryonic development signal transduction cell growth regulation transforming growth factor beta receptor activity
gptkbp:cellularComponent	gptkb:plasma_membrane
gptkbp:domain	Zona pellucida-like domain Serine/threonine-protein kinase domain
gptkbp:encodedBy	TGFBR3 gene
gptkbp:expressedIn	many tissues
gptkbp:function	coreceptor for TGF-beta ligands
gptkbp:gene	gptkb:TGFBR3
gptkbp:glycosylation	yes
https://www.w3.org/2000/01/rdf-schema#label	TGF-beta receptor type III
gptkbp:interactsWith	gptkb:TGF-beta_receptor_type_I gptkb:TGF-beta_receptor_type_II
gptkbp:isSolubleIn	yes
gptkbp:length	851 amino acids
gptkbp:locatedIn	gptkb:cell_membrane
gptkbp:locatedOnChromosome	chromosome 1p32
gptkbp:modulatedBy	apoptosis angiogenesis cell migration cell adhesion
gptkbp:molecularWeight	~100 kDa
gptkbp:mutationAssociatedWith	gptkb:cancer congenital heart defects
gptkbp:OMIM	600069
gptkbp:orthologInMouse	Tgfbr3
gptkbp:PDB	2PJY
gptkbp:regulates	gptkb:TGF-beta_signaling_pathway
gptkbp:reviewedBy	gptkb:GeneCards gptkb:NCBI_Gene gptkb:HGNC gptkb:OMIM gptkb:UniProt gptkb:Ensembl
gptkbp:species	gptkb:Homo_sapiens
gptkbp:UniProtID	Q03167
gptkbp:bfsParent	gptkb:TGF-beta_receptor gptkb:TGF-beta
gptkbp:bfsLayer	7