|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alias
|
MIG5
MRD48
TC25
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:cancer
melanoma
neurodevelopmental disorders
mental retardation
|
|
gptkbp:biologicalProcess
|
GTP binding
GTPase activity
|
|
gptkbp:encodedBy
|
gptkb:RAC1_gene
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000136238
|
|
gptkbp:fullName
|
Rac family small GTPase 1
|
|
gptkbp:function
|
cell proliferation
cell migration
cell adhesion
regulation of actin cytoskeleton
regulation of reactive oxygen species
|
|
gptkbp:gene
|
gptkb:RAC1
|
|
gptkbp:HGNC_ID
|
HGNC:9801
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
RAC1
|
|
gptkbp:interactsWith
|
gptkb:PAK1
gptkb:TIAM1
gptkb:DOCK180
gptkb:IQGAP1
gptkb:NADPH_oxidase_complex
|
|
gptkbp:length
|
192
|
|
gptkbp:locatedOnChromosome
|
7p22.1
|
|
gptkbp:member
|
gptkb:Rho_family_of_GTPases
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Rac1
|
|
gptkbp:pathway
|
gptkb:MAPK_signaling_pathway
gptkb:PI3K-Akt_signaling_pathway
gptkb:Wnt_signaling_pathway
|
|
gptkbp:PDB
|
gptkb:1MH1
2P2L
3TH5
|
|
gptkbp:postTranslationalModification
|
prenylation
phosphorylation
|
|
gptkbp:regulates
|
gene expression
cell polarity
endocytosis
lamellipodia formation
|
|
gptkbp:subcellularLocation
|
gptkb:cytoplasm
gptkb:plasma_membrane
|
|
gptkbp:UniProtID
|
gptkb:P63000
|
|
gptkbp:bfsParent
|
gptkb:PAK1
gptkb:RAC_(Ras-related_C3_botulinum_toxin_substrate)
gptkb:CDC42
gptkb:MAP3K1
gptkb:PRKCZ
gptkb:Grupo_Godó
gptkb:Rac_protein
|
|
gptkbp:bfsLayer
|
7
|