Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:gene |
| gptkbp:alternativeName |
DOCK1
Dedicator of cytokinesis 1 |
| gptkbp:associatedWith |
cancer progression
|
| gptkbp:discoveredBy |
Hasegawa et al.
|
| gptkbp:discoveredIn |
1996
|
| gptkbp:domain |
DHR-1 domain
DHR-2 domain |
| gptkbp:encodedBy |
DOCK1 gene
|
| gptkbp:Entrez_Gene_ID |
1793
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
guanine nucleotide exchange factor
|
| https://www.w3.org/2000/01/rdf-schema#label |
DOCK180
|
| gptkbp:interactsWith |
gptkb:Rac1
gptkb:ELMO1 |
| gptkbp:involvedIn |
cell migration
phagocytosis regulation of small GTPases |
| gptkbp:locatedOnChromosome |
chromosome 10q26.2
|
| gptkbp:molecularWeight |
~180 kDa
|
| gptkbp:OMIM |
601403
|
| gptkbp:orthologIn |
gptkb:Mus_musculus
gptkb:Drosophila_melanogaster |
| gptkbp:regulates |
actin cytoskeleton
cell adhesion |
| gptkbp:UniProtID |
Q14185
|
| gptkbp:bfsParent |
gptkb:Rac1
gptkb:Rac3 gptkb:Rac_protein |
| gptkbp:bfsLayer |
7
|