Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:activatedBy |
phosphorylation of cytosolic subunits
|
| gptkbp:alternativeName |
NOX2 complex
|
| gptkbp:associatedWith |
innate immunity
|
| gptkbp:biologicalProcess |
respiratory burst
|
| gptkbp:component |
gptkb:gp91phox
gptkb:Rac1 p22phox p40phox p67phox p47phox |
| gptkbp:discoveredBy |
Bernard Babior
|
| gptkbp:EC_number |
1.6.3.1
|
| gptkbp:foundIn |
gptkb:eosinophils
macrophages monocytes neutrophils |
| gptkbp:function |
production of reactive oxygen species
|
| gptkbp:gene |
gptkb:CYBA
gptkb:NCF1 gptkb:NCF2 gptkb:NCF4 gptkb:CYBB |
| https://www.w3.org/2000/01/rdf-schema#label |
NADPH oxidase complex
|
| gptkbp:inhibitedBy |
apocynin
DPI (diphenyleneiodonium) |
| gptkbp:location |
phagocyte membrane
|
| gptkbp:product |
gptkb:superoxide_anion
|
| gptkbp:role |
gptkb:chronic_granulomatous_disease
|
| gptkbp:substrate |
NADPH
|
| gptkbp:bfsParent |
gptkb:RAC_(Ras-related_C3_botulinum_toxin_substrate)
gptkb:Rac2 |
| gptkbp:bfsLayer |
7
|