|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:activatedBy
|
guanine nucleotide exchange factors (GEFs)
|
|
gptkbp:biologicalProcess
|
GTP binding
GTPase activity
|
|
gptkbp:decommissioned
|
GTPase-activating proteins (GAPs)
|
|
gptkbp:discoveredIn
|
1980s
|
|
gptkbp:foundIn
|
eukaryotes
|
|
gptkbp:GO_term
|
GO:0007264
|
|
gptkbp:hasKEGGPathway
|
hsa04015
|
|
gptkbp:hasUniProtCategory
|
gptkb:Rho_GTPases
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Rho family of GTPases
|
|
gptkbp:involvedIn
|
signal transduction
wound healing
cancer progression
neuronal development
immune cell function
cellular morphogenesis
|
|
gptkbp:member
|
gptkb:RhoA
gptkb:Rac1
gptkb:Cdc42
gptkb:Rac2
gptkb:Rac3
gptkb:RhoB
gptkb:RhoC
gptkb:RhoD
gptkb:RhoF
gptkb:RhoG
gptkb:RhoH
gptkb:RhoU
gptkb:RhoV
gptkb:Rnd1
gptkb:Rnd2
gptkb:Rnd3
RhoBTB1
RhoBTB2
RhoJ
RhoQ
RhoT1
RhoT2
|
|
gptkbp:namedAfter
|
Ras homologous
|
|
gptkbp:PDB
|
yes
|
|
gptkbp:regulates
|
gptkb:guanine_nucleotide_dissociation_inhibitors_(GDIs)
gene expression
cell cycle progression
cell migration
cell polarity
actin cytoskeleton
cell adhesion
|
|
gptkbp:subclassOf
|
small molecule
|
|
gptkbp:bfsParent
|
gptkb:RAC_(Ras-related_C3_botulinum_toxin_substrate)
gptkb:RAC_(gene)
gptkb:RhoE
gptkb:Rac2
gptkb:Rac3
gptkb:RhoF
gptkb:RhoH
gptkb:Rac_protein
|
|
gptkbp:bfsLayer
|
7
|