|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alias
|
KIAA0051
p195
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:cancer
|
|
gptkbp:discoveredBy
|
1994
|
|
gptkbp:domain
|
gptkb:WW_domain
IQ domain
calponin homology domain
RasGAP-related domain
|
|
gptkbp:encodedBy
|
IQGAP1 gene
|
|
gptkbp:Entrez_Gene_ID
|
ENSG00000117226
GC01M047282
|
|
gptkbp:expressedIn
|
many tissues
|
|
gptkbp:function
|
signal transduction
cell adhesion
regulation of cytoskeleton
scaffolding protein
|
|
gptkbp:gene
|
gptkb:IQGAP1
|
|
gptkbp:HGNC_ID
|
HGNC:6100
|
|
gptkbp:highest_expression
|
gptkb:testis
brain
liver
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
IQGAP1
|
|
gptkbp:interactsWith
|
gptkb:calmodulin
gptkb:CDC42
gptkb:RAC1
gptkb:beta-catenin
gptkb:E-cadherin
CLIP170
|
|
gptkbp:length
|
1657
|
|
gptkbp:locale
|
gptkb:cell_membrane
gptkb:cytoplasm
|
|
gptkbp:locatedOnChromosome
|
gptkb:15q26.1
|
|
gptkbp:molecularWeight
|
190 kDa
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Iqgap1
|
|
gptkbp:PDB
|
available
|
|
gptkbp:phosphorylates
|
yes
|
|
gptkbp:RefSeq
|
NM_003870
|
|
gptkbp:regulates
|
gptkb:MAPK_signaling_pathway
actin cytoskeleton
cell-cell adhesion
|
|
gptkbp:relatedTo
|
cell proliferation
cell migration
cell polarity
|
|
gptkbp:UniProtID
|
P46940
|
|
gptkbp:bfsParent
|
gptkb:RAC_(Ras-related_C3_botulinum_toxin_substrate)
gptkb:CDC42
gptkb:Rac1
gptkb:Cdc42
gptkb:Rac3
gptkb:Rac_protein
|
|
gptkbp:bfsLayer
|
7
|