Neuroblastoma RAS viral oncogene homolog

URI: https://gptkb.org/entity/Neuroblastoma_RAS_viral_oncogene_homolog
GPTKB entity
Statements (32)
Predicate Object
gptkbp:instanceOf gptkb:gene
gptkbp:abbreviation gptkb:NRAS
gptkbp:alternativeName gptkb:neuroblastoma_RAS_oncogene_homolog
gptkb:NRAS_proto-oncogene,_GTPase
gptkbp:associatedWith gptkb:acute_myeloid_leukemia
colorectal cancer
melanoma
thyroid carcinoma
gptkbp:discoveredBy Shimizu et al.
gptkbp:discoveredIn 1983
gptkbp:encodes gptkb:NRAS_protein
gptkbp:Entrez_Gene_ID gptkb:ENSG00000213281
4893
gptkbp:expressedIn various tissues
gptkbp:function signal transduction
GTPase activity
gptkbp:geneType protein-coding
gptkbp:HGNC_ID 7989
https://www.w3.org/2000/01/rdf-schema#label Neuroblastoma RAS viral oncogene homolog
gptkbp:locatedOnChromosome 1p13.2
chromosome 1
gptkbp:memberOf gptkb:RAS_gene_family
gptkbp:mutationAssociatedWith uncontrolled cell proliferation
oncogenic mutation
gptkbp:OMIM 164790
gptkbp:orthologInMouse gptkb:Nras
gptkbp:pathway gptkb:RAS_signaling_pathway
gptkb:MAPK/ERK_pathway
gptkb:PI3K/AKT_pathway
gptkbp:UniProtID gptkb:P01111
gptkbp:bfsParent gptkb:NRAS
gptkbp:bfsLayer 5