|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:MAP_kinase_kinase_kinase
MEKK
|
|
gptkbp:contains
|
gptkb:MAP3K12
gptkb:MAP3K1
gptkb:MAP3K10
gptkb:MAP3K11
gptkb:MAP3K13
gptkb:MAP3K14
gptkb:MAP3K2
gptkb:MAP3K3
gptkb:MAP3K4
gptkb:MAP3K5
gptkb:MAP3K6
gptkb:MAP3K7
gptkb:MAP3K8
gptkb:MAP3K9
|
|
gptkbp:downstreamOf
|
gptkb:MAP2K
receptor signaling
|
|
gptkbp:enzymeClassification
|
serine/threonine protein kinase
|
|
gptkbp:foundIn
|
eukaryotes
|
|
gptkbp:fullName
|
gptkb:Mitogen-activated_protein_kinase_kinase_kinase
|
|
gptkbp:function
|
phosphorylates MAP2K proteins
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
MAP3K
|
|
gptkbp:involvedIn
|
cell proliferation
differentiation
inflammation
apoptosis regulation
cellular response to stress
|
|
gptkbp:proteinFamily
|
MAPK cascade genes
|
|
gptkbp:regulates
|
activated by growth factors
activated by cytokines
activated by environmental stress
activated by small GTPases
|
|
gptkbp:roleInPathway
|
MAPK signaling cascade
|
|
gptkbp:bfsParent
|
gptkb:MAPKKK
gptkb:MAPK_pathway
gptkb:MAPK/JNK_pathway
gptkb:MAP_kinase_kinase_kinase
|
|
gptkbp:bfsLayer
|
7
|