Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:activatedBy |
gptkb:receptor_tyrosine_kinases
protein-protein interactions small GTPases |
| gptkbp:alsoKnownAs |
gptkb:MAP3K
|
| gptkbp:contains |
serine/threonine kinase domain
|
| gptkbp:downstreamOf |
gptkb:MAP_kinase_kinase_(MAP2K)
gptkb:MAP_kinase_(MAPK) |
| gptkbp:enzymeClassification |
EC 2.7.11.25
|
| gptkbp:example |
gptkb:TAK1
gptkb:ZAK gptkb:BRAF gptkb:RAF1 gptkb:DLK gptkb:MEKK1 ASK1 MLK3 TAO1 TPL2 |
| gptkbp:foundIn |
eukaryotes
|
| gptkbp:function |
phosphorylates MAP kinase kinase (MAP2K)
|
| https://www.w3.org/2000/01/rdf-schema#label |
MAP kinase kinase kinase
|
| gptkbp:involvedIn |
gptkb:MAPK_signaling_pathway
|
| gptkbp:proteinFamily |
MAP3K family
|
| gptkbp:regulates |
cellular responses to cytokines
cellular responses to growth factors cellular responses to stress |
| gptkbp:role |
apoptosis
cell proliferation differentiation inflammation |
| gptkbp:bfsParent |
gptkb:MAP_kinase_pathway
|
| gptkbp:bfsLayer |
6
|