Mitogen-activated protein kinase kinase kinase
GPTKB entity
Statements (20)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:abbreviation |
gptkb:MAP3K
|
| gptkbp:alternativeName |
gptkb:MAPKKK
gptkb:MAP_kinase_kinase_kinase MEKK |
| gptkbp:domain |
protein kinase domain
|
| gptkbp:enzymeCommissionNumber |
EC 2.7.11.25
|
| gptkbp:foundIn |
eukaryotes
|
| gptkbp:function |
phosphorylates MAP kinase kinase (MAP2K)
initiates MAPK signaling cascade |
| https://www.w3.org/2000/01/rdf-schema#label |
Mitogen-activated protein kinase kinase kinase
|
| gptkbp:involves |
gptkb:MAPK_signaling_pathway
|
| gptkbp:proteinFamily |
MAP3K family
|
| gptkbp:regulates |
apoptosis
cell differentiation cell proliferation stress response |
| gptkbp:substrate |
gptkb:MAP2K
|
| gptkbp:bfsParent |
gptkb:MAPKKK
|
| gptkbp:bfsLayer |
7
|